ABSTRACT
Objective: To compare the healing effects of dried and acellular human amniotic membrane and Mepitel for coverage of split-thickness graft donor site [STGDS]
Methods: Twenty patients who underwent STGDS regeneration surgery in identical anatomic regions were enrolled in this randomized controlled clinical trial conducted in Hazrate Fatemeh hospital [Iran]. Patients were randomly assigned in 3 groups of wound dressing; group A by Mepitel, group B AmiCare [Dried amniotic membrane] and group C OcuReg-A [Acellular amniotic membrane]. Re-epithelization rate [healing time], pain sensation, scar formation and infection rate were assessed till complete healing was achieved
Results: Our results showed no significant difference between Amicare, OcuReg-A and Mepitel in the features analyzed by us including: Re-epithelization rate [healing time] p=0.573, Pain sensation p=day 4[th]: 0.131, day 8[th]: 0.93 and day 12[th]: 0.365, Scar formation p>0.05 and Infection rate
Conclusion: Our findings confirmed the safety and efficacy of Ami Care [dried amniotic membrane] and OcuReg-A [Acellular amniotic membrane] in treatment of split-thickness donor site in comparison with Mepitel as a standard wound dressing. Trial registration number: IRCT201511118177N12
ABSTRACT
Background and Aim: Massage can produce sense of security, enhanced physical growth, improved circulation and function of nervous system. It also can decrease sleep disorders and behavior disturbances. This study investigated the effect of massage on intra ventricular hemorrhage in premature infants in the neonatal intensive care unit [NICU] of Ghaem Hospital in Mashhad, Iran
Material and Methods: In this random clinical trial 60 stable preterm newborns were divided into intervention [n=30] and control [n=30] groups. The intervention group performed passive massage movements for three short periods [each period= fifteen minutes] in 3 consecutive hours for 5 days. The intervention and control groups were compared with each other in regard to the incidence of intra ventricular hemorrhage. Our tools for data collection included forms for sample selection and demographic characteristics, check lists to record data and pulse oximetry device. Using SPSS.16 software, data were analyzed by independent t-test, chi square test and odds ratio
Results: In our study experimental group showed a lower incidence rate of intra ventricular hemorrhage in comparison to the control group [P= 0.058]; however, it was not statically significant
Conclusion: According to the results of this study massage along with other methods can be an effective method for reducing the incidence of intra ventricular hemorrhage in stable premature infants